New preprint on how the lectin domain of LORE binds its fatty acid ligands
Lin-Jie Shu and colleagues identify the second G-type lectin domain of LORE as the ligand binding domain, and describe a flexible loop that lets the receptor distinguish agonistic from antagonistic 3-hydroxy fatty acids. Joint work with the group of Antonella Di Pizio at the Leibniz Institute for Food Systems Biology.